The browser you are using is not supported by this website. All versions of Internet Explorer are no longer supported, either by us or Microsoft (read more here: https://www.microsoft.com/en-us/microsoft-365/windows/end-of-ie-support).

Please use a modern browser to fully experience our website, such as the newest versions of Edge, Chrome, Firefox or Safari etc.

New study shows how dementia affects the brain's ability to empathise

Brain scan. Picture.
Dementia usually means memory problems, but frontotemporal dementia with a loss of ability to empathize with other people can resemble other conditions with empathy problems in psychiatry, such as psychopathy. Photo:Mostphotos

Patients with frontotemporal dementia often lack the ability to empathize. A study at Lund University and Karolinska Institutet has now shown that these patients do not show the same brain activity as healthy individuals when they witness the pain of others, a finding that it is hoped will increase understanding of this specific dementia disease.

This is an important piece of the puzzle now falling into place, as we can see how individuals with frontotemporal dementia experience empathy," says Alexander Santillo, researcher and associate professor of psychiatry at MultiPark, Lund University and senior consultant in psychiatry.

Around 25 000 Swedes are affected by dementia every year. Of these, about three percent are diagnosed with frontotemporal dementia. The disease is difficult to diagnose, but one of its characteristics is that sufferers lose the ability to empathize, which can lead to problems for them, and not least for their relatives.

In the current study, led by researchers Olof Lindberg at Karolinska Institutet and Alexander Santillo at MultiPark, Lund University, 28 patients diagnosed with frontal lobe dementia were analyzed using functional magnetic resonance imaging (fMRI). 

The researchers were able to see how the subjects' brain activity was affected when they were shown images of hands being penetrated by needles, which normally activates the parts of the brain that tend to react to the experience of suffering or pain in others.

Hands touched in different ways. Photo.
Typical images that the study participants could see. Photo: Olof Lindberg.

The study shows that people with frontotemporal dementia do not display any activation of the frontal brain networks that are activated in the control group of age-matched healthy individuals.

Read the press release (From KI). 

This study was funded by ALF, The Bundy Academy, The Schörling Foundation, and The Åke Wiberg Foundation.